Elastic Hard Drive Noise Reduction Hack
Check out this simple yet effective way to keep the noise from your hard drives to a minimum. The one downside to this hack is that you lose the passive cooling that was occurring when the drives were attached to your case. Also, you’ll either have to use up your optical drive bays, buy smaller hard drives, or make a custom drive cage to do this.

As the pictures show, the drive is essentially suspended on the stretched elastic. The resilience of the elastic stops all vibrations from passing from the drive to the case — or vice versa, for that matter. The drive cage was rigged it up with two Barracuda drives (20G & 40G) and installed with a couple of machine screws at the bottom of my main PC with a decoupled low power 80mm fan in front of it (at the front panel intake hole).
Via Make Via Slash Gear

*Reduction*
Billy Thx for the correction